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Unravelling the Diphtheria Crisis in Khyber-Pakhtunkhwa

Diphtheria crisis in KPK

Unravelling the Diphtheria Crisis in Khyber-Pakhtunkhwa: Navigating a Global Legacy of Disease and A Call to Solution
In the shadow of the COVID-19 and dengue battles, Khyber-Pakhtunkhwa (KP) is now confronting a grave outbreak of diphtheria, marking a sombre chapter in the province’s health history. With 16 lives lost and 328 individuals infected across 28 districts between January and October, the urgency to address longstanding issues in vaccination efforts and healthcare infrastructure becomes more pressing than ever.
It is essential to recognize the global historical context of this infectious disease. Diphtheria, a bacterial infection caused by Corynebacterium diphtheriae, has left an indelible mark on public health worldwide. Understanding its historical trajectory offers insights into the urgency of addressing the current crisis.
Global Historical Context
Diphtheria has been a recurring threat throughout history, with devastating consequences for populations around the world. Before the advent of widespread vaccination, particularly in the late 19th and early 20th centuries, diphtheria was a leading cause of mortality among children.
In the late 1800s, the introduction of the diphtheria antitoxin marked a significant advancement in treatment. However, preventive measures, such as vaccination, only gained prominence in the mid-20th century. The development and widespread use of the diphtheria-tetanus-pertussis (DTP) vaccine played a crucial role in reducing the incidence of diphtheria globally.
Impact on Global Health
Prior to the widespread implementation of vaccination programs, diphtheria outbreaks were particularly devastating in densely populated areas and among communities with limited access to healthcare. The disease’s hallmark symptom, a thick grayish coating in the throat and respiratory tract, often led to respiratory failure and death.
Efforts to control diphtheria intensified in the mid-20th century, and the incorporation of the DTP vaccine into routine immunization schedules contributed to a substantial decline in diphtheria cases globally. The World Health Organization (WHO) has been instrumental in advocating for and facilitating vaccination programs to curb the spread of the disease.
Present Challenges in Khyber-Pakhtunkhwa
Despite significant progress in reducing diphtheria on a global scale, the recent outbreak in Khyber-Pakhtunkhwa highlights persistent challenges, including inadequate vaccination efforts and a shortage of essential medical resources. This serves as a stark reminder that infectious diseases, even those with available vaccines, can resurface and wreak havoc if preventive measures falter.
Causes
The diphtheria outbreak’s roots lie in historical failures to immunize children adequately. Although the immunization rate for children under two stands at 90 percent across the province, adults and the elderly remain vulnerable due to past lapses in vaccination campaigns. Shockingly, 89 percent of reported diphtheria cases across all age groups have no history of vaccination.

The scarcity of the anti-diphtheria serum is compounding the crisis, essential for treating the disease. Major healthcare facilities lack this crucial serum, and the international supply chain, predominantly reliant on India and Russia, is both unreliable and time-consuming.
Way forward
Intensification of Vaccination Efforts
• Launching comprehensive vaccination campaigns targeting both children and adults, learning from past shortcomings.
• Utilization of the electronic immunization registration system to monitor and manage vaccinations for all children.
• Addressing vaccine hesitancy among parents through targeted awareness programs.
• Ensuring a Stable Supply of Anti-Diphtheria Serum:
• Collaboration with international organizations to establish a sustainable supply chain for the anti-diphtheria serum.
• Exploration of domestic production or alternative sources to reduce dependence on a limited international supplier.
• Inclusion of anti-diphtheria serum in the list of essential medicines procured for all hospitals, irrespective of their immunization program status.
Implementation of Robust Preventive Measures
• Drawing lessons from successful preventive measures implemented during the caretaker government’s tenure.
• Allocating resources strategically to support proactive preventive measures, considering existing financial constraints.
• Collaboration with international organizations to conduct research on the root causes of the outbreak and develop targeted interventions.
Conclusion
The diphtheria outbreak in Khyber-Pakhtunkhwa is not merely a current crisis; it is intertwined with a history marked by the toll of infectious diseases. Urgent action is imperative to address issues in vaccination efforts and healthcare infrastructure. The lives lost to diphtheria serve as a poignant reminder of the province’s health struggles, emphasizing the need for swift, strategic, and sustained action to protect the well-being of its citizens and pave the way for a healthier future.

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